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Breast cancer Proteogenomics

Faculty of Medicine / Department of Clinical Sciences, Lund / Section I / Biomarkers and epidemiology

Visiting address: Sölvegatan 19, BMC, 22184 Lund

Breast cancer Proteogenomics' profile in Lund University Research portal

Description

Breast cancer is affecting every tenth woman. Local recurrences (LR) indicate an increased risk of distant recurrences (DR) and mortality and might be the first sign towards a spread disease. Prediction of LR could therefore be crucial, an issue we attempt to address. The overall aim within the group is to predict recurrences by monitoring breast cancer specific proteins in tumors and patient blood, primarily using a combination of the DNA sequence and mass spectrometric analysis and to translate these findings into clinical routine work. The proteogenomic strategy will enable us to identify biomarker profiles that predict LR which will be validated by immunohistochemistry (TMA) in additional tumor material and by mass spectrometry of blood samples. We hope that these approaches will uncover breast cancer specific changes that will define new biomarkers distinguishing patients with an increased risk of developing LR.

Staff

A

  • Noor Alturaihi

    Research project participant

    noor [dot] alturaihi [at] med [dot] lu [dot] se

D

  • Tommaso de Marchi

    Research project participant

    tommaso [dot] de_marchi [at] med [dot] lu [dot] se

E

  • Moa Egelberg

    Research project participant

    moa [dot] egelberg [at] med [dot] lu [dot] se

G

  • Anna Gardfjell

    Research project participant

    anna [dot] gardfjell [at] med [dot] lu [dot] se

N

  • Emma Niméus

    Project manager

    emma [dot] nimeus [at] med [dot] lu [dot] se

P

  • Gyula Pekar

    Research project participant

    gyula [dot] pekar [at] med [dot] lu [dot] se

  • Paul Theodor Pyl

    Research project participant

    paul_theodor [dot] pyl [at] med [dot] lu [dot] se

R

  • Susanne Reinsbach

    Research project participant

    susanne [dot] reinsbach [at] med [dot] lu [dot] se

S