The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Multidimensional microstructure imaging

Faculty of Medicine / Department of Clinical Sciences, Lund / Section V / Diagnostic Radiology, (Lund)

Visiting address: Centralblocket, SUS, Lund, plan 4, 221 85 Lund

Service point: 32

Multidimensional microstructure imaging's profile in Lund University Research portal

Description

In diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflect cell density and the orientation coherence of tissue, in terms of the mean diffusivity (MD) and fractional anisotropy (FA), respectively. However, these metrics conflates multiple measures of the microstructure. In our group, we are developing a novel set of technologies for acquisition and analysis of dMRI that we collectively call multidimensional microstructure imaging (MMI). MMI takes advantage of our recent developments for dMRI that enables diffusion encoding by gradient waveforms that goes beyond previous strategies, such as so-called single diffusion encoding.

Staff

C

  • Arthur Chakwizira

    Research project participant

    arthur [dot] chakwizira [at] med [dot] lu [dot] se

L

  • Björn Lampinen

    Research project participant

    bjorn [dot] lampinen [at] med [dot] lu [dot] se

  • Samo Lasic

    Research project participant

    samo [dot] lasic [at] med [dot] lu [dot] se

M

N

  • Markus Nilsson

    Project manager

    markus [dot] nilsson [at] med [dot] lu [dot] se

S