The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Schmidtchen Lab

Faculty of Medicine / Department of Clinical Sciences, Lund / Section III / Dermatology and Venereology (Lund)
Schmidtchen Lab's profile in Lund University Research portal

Description

Bacterial infections spanning from local wound infections, affecting patients with non-healing leg ulcers, postoperative wounds or burns, to severe infections and sepsis, are significant medical problems. Today's anti-infective treatments do not address the excessive activation of inflammatory pathways during infection and sepsis, and resistance problems are increasing. Hence, there is a huge unmet need for novel therapies that go beyond mere classical antibacterial effects, and which also selectively modulate both pro- and anti-inflammatory pathways during infections. The purpose of our research is to define and utilize new knowledge on innate immunity, with a focus on endogenous antimicrobial and immunomodulatory peptides and proteins, in order to develop the next generation's anti-infective treatments, with potential applications for skin infections and burns, postoperative profylaxis, but also for invasive infections and sepsis.

Staff

S