Lund University logotype, link to Lund University
Denna webbplats på svenska
Listen

The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Neural stem cells

Faculty of Medicine / Department of Experimental Medical Science
Website: https://www.stemcellcenter.lu.se/research-groups/falk

Visiting address: Sölvegatan 19, 221 84 Lund

Postal address: Box 118, 221 00 Lund

Service point: 66

Neural stem cells' profile in Lund University Research portal

Description

Reprogramming somatic cells to induced pluripotent stem (iPS) cells and directed differentiation opens up for studies on neural cells from patients. The Falk group is focusing on fundamental questions in early human neurogenesis. We build cellular models of the healthy and diseased human brain using reprogrammed patient cells. We derive patient specific iPS cells that are further differentiated into patient specific neuroepithelial stem (NES) cells or into 3D brain organoids. We use the cellular models to study proliferation, self-renewal, and differentiation potential as well as the maturation and function of derived neurons to uncover disease mechanisms. The Neural Stem Cells lab is also driving translational projects investigating the regenerative potential of iPS cell derived neural cells in preclinical models with the aim to create ATMPs to take iPS derived cell to clinic. We have derived one of few clinical compliant GMP iPS cell lines that we have banked in a master bank.

Coworkers

E

  • Ilse Eidhof

    Visiting research fellow

    ilse [dot] eidhof [at] med [dot] lu [dot] se

F

P

S

T

  • Daniel Twohig

    Postdoctoral fellow

    daniel [dot] twohig [at] med [dot] lu [dot] se

W

  • Tamina Weiss

    Student working on a degree project

    tamina [dot] weiss [at] med [dot] lu [dot] se

  • Dania Winn

    Visiting research fellow

    dania [dot] winn [at] med [dot] lu [dot] se